When it comes email signatures that gets noticed above others (such as for business purposes), most people do it the wrong way.
The wrong way is to add in big images, huge text, crazy fonts or some other such nonsense.
Getting an email signature noticed can be done easily by simply using non-standard ways of how they’re displayed. And the fortunate part is that all of what’s below can be done in just about any major webmail provider’s signature editor.
1. Justify to the right
This is how the end of a printed letter usually ends, so it works very well in email. Given the fact that just about everyone has their signature on the left, having yours on the right is a ridiculously easy way to get noticed, even if all the text is plain and not styled.
2. Using a teletype font
For most of you, this means using the font "Courier New" for your signature.
This gets noticed mainly for the reason most people never use a teletype font in email these days.
3. Surround in brackets
If your signature is short enough to fit on a single line, using brackets gets noticed because it gives the subtle hint that you should read it.
4. "Highlight" your name
This one involves a feature of webmail that almost nobody uses – setting a background color for text.
All you’re doing here is giving the appearance that your name is highlighted. Again, this is subtle but it works very well. Place a space before an after your name, select the line and then simply set a background color.
Note for Hotmail users
The Hotmail signature editor does not have a button where you can select a background color, but you can edit the HTML code manually do to the same thing.
How it’s done is like this:
First, while in the signature editor, choose to Edit in HTML.
Second, copy and paste this line of code into your signature editor.
<font style="background-color: #ffc000">-Your Name-</font><br>you@example.com<br>www.yourweb.site
Third, in the signature editor, switch back to "Rich Text", and you’ll end up with this:
Replace the appropriate text with the information you want to show, adjust font and font size to suit, then save.
The gold background color is the #ffc000 portion of the code. If you’d like to use a different color, a huge chart is here listing a ton of them. The hexadecimal color codes will be on the right.
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In some circles of corporations, a signature is always on the lower right. I do this on some occasions for the reasons you stated. This was standard practice before computers and taught at schools everywhere but started to die out around the 1990′s.