If you consistently have a bunch of tabs open when using Firefox, one problem you may have is following the ‘breadcrumb’ of how tabs relate to each other. For example, if you are looking at search results on troubleshooting and then follow a link which opens a new tab and follow another link which opens another new tab (etc., etc.), the tabs can be cumbersome to backtrack. To help with this, check out the Tree Style Tab add-on:
This provides tree-style tab bar, like a folder tree of Windows Explorer. New tabs opened from links (or etc.) are automatically attached to the current tab. If you often use many many tabs, it will help your web browsing because you can understand relations of tabs.
Their explanation hopefully clarifies my example, but checkout the screenshots on the link and you will see exactly what it does.
I find this particularly useful when researching code documentation because I can jump back and forth between my search results and any message boards and articles I opened from there.

Jason Faulkner is the man who brings you our daily tips. He is based in Atlanta, Georgia.
I’ve been using this extension for quite some time now and I love it! I actually changed my tabs to the left hand side of my screen though as you can list them more efficiently that way. It uses a little bit of screen real estate (depending on how wide you make the tab window) but on a 22″ screen it’s not a big deal. It’s much easier to see all your tabs opened in a list form vs having to scroll across the top and then click an arrow button to see the rest.
Highly recommend this one also.
I have the same setup as Drew. I highly recommend the addon to any widescreen user.