Most people know that they can create a shortcut on your desktop to any program by right-clicking, choosing New > Shortcut. An often overlooked feature of this dialog box, though, is the shortcut key combination. Basically, you can enter any key combination into the Shortcut Key field by simply putting the cursor in that field and then actually performing the key combination you want. You will see the combination appear in the field box. If the combination you choose is already in use, Windows will put something similar into place (such as the Alt button). After saving your changes, you can perform that key combination and the shortcut will execute, opening up the program it leads to.

This is a nice way to customize your PC and get quick access to your stuff.