After updating Spybot Search and Destroy’s definition file, it is possible that there are new items for the immunization list. By default, simply downloading the latest updates isn’t enough to add any new items to Spybot’s immunization file and if one wants to take advantage of any new updates to this file, they must once again immunize their computer. After downloading new updates, remember to run Spybot’s immunization function to update it as well.