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On the hardware side:
Almost any commerical grade router can support X.25. I know that Cisco supports this on all current router platforms with the IP only feature pack (which means it is supported on all other feature packs as well).
ATM: This protocol has higher levels of processing power required and there is specialized hardware required to support this protocol (ie AIM-ATM card or other ATM line cards that are model dependant from Cisco) as well as specific IOS feature packs depending on the type of traffic (video, voice etc).
On the software side?
Seeing these are both networking protocols (layer 3/4 or lower on the OSI model), application software (OSI layers 5-7) really do not come into play. When to use these 2 protocols comes into play when analyzing traffic flow on the LAN/WAN. Again, X.25 works well in areas/needs where large blocks of data are moved around (ie remote site data backups to a central site, copying large data blocks from one site to another) but not where there is a lot of back and forth of data (like an order entry system) where latency can be wreak havoc on the transfer. ATM is used when you are 1) looking at a converged network (voice/video and data) where the potential need to move at high speeds may be necessary (ATM is supported up to 600+mpbs, where as IP traffic needs to be converted over to a protocol called SONET at those speeds, but that is changing).
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