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Yes, a motherboard/CPU/RAM combo is supposedly more reliable and less replaceable than therefore can be made proprietary. I have a Dell machine which is a couple of years old, and (at that point anyway) they still made all of the drives (hard, optical, floppy) standard. I would bet it will work fine.
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Desktop
| Antec Performance Plus 1080AMG | Antec 430W PSU | Intel D875PBZ | Intel P4 3.0C |
| 4x512 MB dual-channel DDR400 Kingston HyperX | ATI Radeon 9800 pro 256 MB | Creative Sound Blaster Audigy Gamer |
| LiteOn DVD-ROM | LiteOn CDRW | 36 GB WD Raptor | 250 GB WD SATA2 | Sony Floppy | XP pro |
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