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Old 07-19-2005, 04:24 PM   #1
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just wondering.

I just have 4 boxes folding and I just noticed that 2 of my boxes are both working on the same unit, P890_p53dimer890. a 5000 frame work unit.

Worth 272. I was wondering if I should kill one of them or let it go. What really is the point to have the same work unit run several times? I mean if I have got it twice together, I bet many other people also got the same unit to work.

I know for safeguards have each unit worked several times by different people to compare results, but seems they may be going over board on that a bit.
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Old 07-19-2005, 07:07 PM   #2
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I think it's like "finding the needle in the haystack" in the sense that finding that one protein that mis-folds is the needle so they need thousands of samples to in order to find it.

Here is a partial list of many proteins I've folded more than once.

BTW I just let em' roll cause you'll prolly get the same one again.
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Old 07-19-2005, 07:39 PM   #3
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Well that answers a few more of my questions, I was trying to make heads and tails out of the following link. Now I know that is the proteins. Hey at least i am leaving again. Just bare with me, I have been out of folding for a long time.

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Old 07-19-2005, 11:10 PM   #4
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hey man, we all have to start somewhere, we all ask questions. we will do our best to answer them for ya and if we can't there is always the folding forums....

you asking questions shows me that you really want to learn more about the project and i for one think thats a great thing!
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Old 08-12-2005, 12:54 AM   #5
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Hey guess what?....I am folding p890_p53dimer890 as well! This is my second WU.

Do we get points based on time utilized or work accomplished?...basicly do we get points in proportion to how fast our computers are or not? Or is it a point system where we get a certain number of points per WU?...where if you have a faster computer then you have an advantage?

Is the seconds/frame rate a reflection of how fast your computer is doing the computations? Mine reads 44 seconds/frame.

Is this why they want the same protein folded numerous times?:...from Wikipedia:

Incorrect protein folding and neurodegenerative disease

Incorrectly folded proteins are responsible for prion related illness such as Creutzfeldt-Jakob disease and Bovine spongiform encephalopathy (mad cow disease), and amyloid related illnesses such as Alzheimer's Disease. These diseases are caused by misfolded proteins aggregating into insoluble plaques.

Your right Enhanced..the part about Gromacs core is interesting. I did a Google on it.

I ran across this site http://www.alliancefrancophone.org/psummary.html on Google. It's in French, but its easy to see what the information means.

Also interesting: http://foldy.nozero.org/ Missing data?

I looked up protein folding in Wikipedia and this explanation made more sense to me than the Stanford explanation. http://en.wikipedia.org/wiki/Protein_folding

There is another organization using distributed computing to do science. http://en.wikipedia.org/wiki/Distributed.net Right now they are doing whats called a Golomb rulers. I dont see how that benefits mankind any better than Folding@Home though.
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Last edited by David M; 08-12-2005 at 01:37 AM.
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